Let us be the generation that stands up to cytomegalovirus (CMV), a highly contagious viral infection that can harm an unborn child. Learn more about a clinical trial for a potential vaccine.
ictory Trial
This clinical trial is sponsored by Moderna. Moderna is studying mRNA-1647, an investigational
vaccine to understand whether it can help your immune system protect against cytomegalovirus (CMV).
The purpose of this clinical trial is to:
Cytomegalovirus, shortened to CMV, is a leading cause of birth defects around the world. CMV is a common viral infection that usually goes unnoticed or only causes mild symptoms in most people. But if a woman becomes infected with CMV while she is pregnant, she can pass the infection to her unborn baby. This can cause her child to suffer long-term disability due to birth defects, including hearing loss, or even death in very severe cases. Currently, there is no approved vaccine against CMV.
The total length of participation in this clinical trial is
approximately 2½ years (30 months).
You will be compensated for your time and for each visit you complete. More information about
reimbursement can be found in the expenses section of the Patient Information and Informed Consent Form,
and your clinical trial team can also give you more details.
We will schedule your visits in a way that minimizes disruption to your work and other commitments.
The investigational vaccine may help the body's immune system recognize and protect itself if it comes into contact with CMV in the future. You cannot become infected with CMV from receiving the investigational vaccine. The investigational vaccine in this trial, mRNA-1647, is a newer type of vaccine known as an mRNA vaccine.
Map:
Every virus has signature features on its surface that can trigger your immune
system. Once the features are mapped, an mRNA vaccine provides the blueprint to create the defense that
can help your body protect itself if it encounters the virus.
Read:
Once your body has the blueprint, it knows exactly what to do. It reads mRNA
strands to build a defense by producing antibody proteins that are a lot like the answer key to a test.
This means the next time your immune system encounters this type of virus, it already has the answer to
help protect you.
Neutralize:
Your body now knows how to neutralize the virus and is able to defend
itself against the threat if it encounters the virus in the future. The message from the blueprint that
was read is retained and recalled when needed. It's like remembering the answer from an old test without
having to re-learn the material.
Activate:
Moderna is developing mRNA vaccines, like the investigational vaccine
mRNA-1647, that deliver blueprints to create the proteins that help activate immune responses against
a variety of viruses.
The investigational vaccine may help the body's immune system recognize and protect itself if it comes into contact with CMV in the future. You cannot become infected with CMV from receiving the investigational vaccine. The investigational vaccine in this trial, mRNA-1647, is a newer type of vaccine known as an mRNA vaccine.
Map:
Every virus has signature features on its surface that can trigger your immune
system. Once the features are mapped, an mRNA vaccine provides the blueprint to create the defense that
can help your body protect itself if it encounters the virus.
Read:
Once your body has the blueprint, it knows exactly what to do. It reads mRNA
strands to build a defense by producing antibody proteins that are a lot like the answer key to a test.
This means the next time your immune system encounters this type of virus, it already has the answer to
help protect you.
Neutralize:
Your body now knows how to neutralize the virus and is able to defend
itself against the threat if it encounters the virus in the future. The message from the blueprint that
was read is retained and recalled when needed. It's like remembering the answer from an old test without
having to re-learn the material.
Activate:
Moderna is developing mRNA vaccines, like the investigational vaccine
mRNA-1647, that deliver blueprints to create the proteins that help activate immune responses against
a variety of viruses.
Vaccines aim to safely protect people against infections, and clinical trials are vital to creating vaccines. A clinical Trial can help researchers understand whether an investigational vaccine is safe and effective. By participating in the CMVictory Trial, you can help create a future where we may hopefully declare victory and prevent the spread of CMV.
Moderna is committed to keeping people at the center of everything we do as we continue to explore what is possible through mRNA science. Without people like you, researching potential new treatments and mRNA vaccines would not be possible.
We are proud to partner with the following groups and organizations in the fight for victory against CMV:
Clinical trial staff will explain any additional requirements and answer any questions you or a loved one may have about participation. You may stop participation in the clinical trial at any time, and you do not have to give a reason for doing so.
Moderna is committed to researching safe and effective mRNA-based vaccines and therapies to bring better health and living to people of all ages, sexes, and backgrounds.
The CMVictory Trial will take place at locations (or sites) all around the world. Use this site locator to search for the site closest to you—as well as their contact information.
Noble Clinical Research - Tuscon
Tucson, Arizona United States 85704
Hope Research Institute LLC - Hunt - PPDS - Peoria
Peoria, Arizona United States 85381
Hope Research Institute LLC - Hunt - PPDS - Tempe
Tempe, Arizona United States 85284
Hope Research Institute LLC - Hunt - PPDS - Phoenix
Phoenix, Arizona United States 85018
Preferred Research Partners - ClinEdge - Little Rock
Little Rock, Arkansas United States 72211
Paradigm Clinical Research Institute Inc - La Mesa
La Mesa, California United States 91942
Velocity Clinical Research - San Diego - ERN - PPDS
La Mesa, California United States 91942
Paradigm Clinical Research Institute Inc - Redding
Redding, California United States 96001
Velocity Clinical Research - Banning - ERN - PPDS
Banning, California United States 92220
Velocity Clinical Research - Chula Vista - ERN - PPDS
Chula Vista, California United States 91911
Clinical Research Consultants LLC - ClinEdge - PPDS
Milford, Connecticut United States 06460
Precision Clinical Research - Coral Springs - ClinEdge - PPDS
Sunrise, Florida United States 33351
Riverside Clinical Research
Edgewater, Florida United States 32132
CVS Health Hub - Newnan
Newnan, Georgia United States 30265
iResearch Atlanta - Decatur
Decatur, Georgia United States 30030
Tekton Research - Georgia - Platinum - PPDS
Chamblee, Georgia United States 30341
Mount Vernon Clinical Research, LLC - M3 WR - ERN - PPDS
Sandy Springs, Georgia United States 30328
CVS Health Hub - Atlanta/ MLK
Atlanta, Georgia United States 30311
CVS Health Hub - Mcdonough
McDonough, Georgia United States 30253
CVS Health Hub - Kennesaw
Kennesaw, Georgia United States 30152
CVS Health Hub - Dacula
Dacula, Georgia United States 30019
CVS Health Hub - Atlanta
Atlanta, Georgia United States 30329
CVS Health Hub - Savannah
Savannah, Georgia United States 31405
Iowa Clinic
West Des Moines, Iowa United States 50233
Heartland Research Associates - Newton
Newton, Kansas United States 67114
Johnson County Clin-Trials
Lenexa, Kansas United States 66219
Meridian Clinical Research (Rockville Maryland) - Platinum - PPDS
Rockville, Maryland United States 20854
ActivMed Practices & Research Inc
Methuen, Massachusetts United States 01844
Clinical Research Institute, Inc.
Minneapolis, Minnesota United States 55402
MedPharmics - Platinum - Gulfport - PPDS
Gulfport, Mississippi United States 39503
MediSync Clinical Research Hattiesburg Clinic
Petal, Mississippi United States 39465
Meridian Clinical Research (Hastings-Nebraska) - Platinum – PPDS
Hastings, Nebaska United States 68901
Meridian Clinical Research (Grand Island) - Platinum – PPDS
Grand Island, Nebraska United States 68803
Quality Clinical Research - HyperCore - PPDS
Omaha, Nebraska United States 68114
Meridian Clinical Research (Norfolk-Nebraska) - Platinum - PPDS
Norfolk, Nebraska United States 68701
Meridian Clinical Research (Omaha-Nebraska) - Platinum - PPDS
Omaha, Nebraska United States 68114
Med Clinic Research Partners, LLC - Irvington
Irvington, New Jersey United States 07111
MedPharmics, LLC. - Albuquerque - Platinum - PPDS
Albuquerque, New Mexico United States 87102
Albuquerque Clinical Trials Inc - Clinedge - PPDS
Albequerque, New Mexico United States 87102
Meridian Clinical Research (Endwell-New York) - Platinum - PPDS
Binghamton, New York United States 13901
Carolina Institute for Clinical Research - M3 WR - ERN - PPDS
Fayetteville, North Carolina United States 28303
M3 Wake Research, Inc - M3 WR - ERN - PPDS
Raleigh, North Carolina United States 27612-8106
Lucas Research
Morehead City, North Carolina United States 28557
Lillestol Research - Hunt - PPDS
Fargo, North Dakota United States 58104
Senders Pediatrics
South Euclid, Ohio United States 44121
PriMed Physicians
Dayton, Ohio United States 45419
Aventiv Research Inc. - Dublin - HyperCore - PPDS
Columbus, Ohio United States 43213
CTI Clinical Research Center - PPDS
Cincinnati, Ohio United States 45212
Meridian Clinical Research - Cincinnati - Platinum - PPDS
Cincinnati, Ohio United States 45219
Tekton Research - Oklahoma - Platinum - PPDS
Yukon, Oklahoma United States 73099
Lynn Health Science Institute - ERN - PPDS
Oklahoma City, Oklahoma United States 73112
Coastal Carolina Research Center
North Charleston, South Carolina United States 29405
DM Clinical Research - ERN - PPDS
Tomball, Texas United States 77375
Premier Family Physicians - Austin - Hunt - PPDS
Austin, Texas United States 78735
Diagnostics Research Group
San Antonio, Texas United States 78229
UTMB Health Pediatric Primary Care - Bay Colony
League City, Texas United States 77573
Village Health Partners Frisco Medical Village
Plano, Texas United States 75024
Velocity Clinical Research - Austin - ERN - PPDS
Cedar Park, Texas United States 78613
Tekton Research - Beaumont - Platinum - PPDS
Beaumont, Texas United States 77706
Tekton Research Inc
Austin, Texas United States 78745
ARC Clinical Research at William Cannon
Austin, Texas United States 78745
Synergy Group US, LLC - Katy - Texas - PPDS
Missouri City, Texas United States 77459
ARC Clinical Research at Wilson Parke - ClinEdge - PPDS
Austin, Texas United States 78726
Austin Regional Clinic ARC Clinical Research at Kelly Lane
Pflugerville, Texas United States 78660
Clinical Trials of Texas, Inc. - PPDS
San Antonio, Texas United States 78229
Velocity Clinical Research - Boise - ERN - PPDS
West Jordan, Utah United States 84088
Tanner Clinic
Layton, Utah United States 84041-8803
Foothill Family Clinic-North Clinic
Salt Lake City, Utah United States 84109
Foothill Family Clinic-Cottonwood Heights
Salt Lake City, Utah United States 84121
Health Research of Hampton Roads Inc. - Clinedge - PPDS
Newport News, Virginia United States 23606
York Clinical Research
Norfolk, Virginia United States 23510
David Ramstad Associates Research - IACT - HyperCore - PPDS
Suffolk, Virginia United States 23435-3763
