Let us be the generation that stands up to cytomegalovirus (CMV), a highly contagious viral infection that can harm an unborn child. Learn more about a clinical trial for a potential vaccine.
ictory Trial
This clinical trial is sponsored by Moderna. Moderna is studying mRNA-1647, an investigational
vaccine to understand whether it can help your immune system protect against cytomegalovirus (CMV).
The purpose of this clinical trial is to:
Cytomegalovirus, shortened to CMV, is a leading cause of birth defects around the world. CMV is a common viral infection that usually goes unnoticed or only causes mild symptoms in most people. But if a woman becomes infected with CMV while she is pregnant, she can pass the infection to her unborn baby. This can cause her child to suffer long-term disability due to birth defects, including hearing loss, or even death in very severe cases. Currently, there is no approved vaccine against CMV.
The total length of participation in this clinical trial is
approximately 2½ years (30 months).
You will be compensated for your time and for each visit you complete. More information about
reimbursement can be found in the expenses section of the Patient Information and Informed Consent Form,
and your clinical trial team can also give you more details.
We will schedule your visits in a way that minimizes disruption to your work and other commitments.
The investigational vaccine may help the body's immune system recognize and protect itself if it comes into contact with CMV in the future. You cannot become infected with CMV from receiving the investigational vaccine. The investigational vaccine in this trial, mRNA-1647, is a newer type of vaccine known as an mRNA vaccine.
Map:
Every virus has signature features on its surface that can trigger your immune
system. Once the features are mapped, an mRNA vaccine provides the blueprint to create the defense that
can help your body protect itself if it encounters the virus.
Read:
Once your body has the blueprint, it knows exactly what to do. It reads mRNA
strands to build a defense by producing antibody proteins that are a lot like the answer key to a test.
This means the next time your immune system encounters this type of virus, it already has the answer to
help protect you.
Neutralize:
Your body now knows how to neutralize the virus and is able to defend
itself against the threat if it encounters the virus in the future. The message from the blueprint that
was read is retained and recalled when needed. It's like remembering the answer from an old test without
having to re-learn the material.
Activate:
Moderna is developing mRNA vaccines, like the investigational vaccine
mRNA-1647, that deliver blueprints to create the proteins that help activate immune responses against
a variety of viruses.
The investigational vaccine may help the body's immune system recognize and protect itself if it comes into contact with CMV in the future. You cannot become infected with CMV from receiving the investigational vaccine. The investigational vaccine in this trial, mRNA-1647, is a newer type of vaccine known as an mRNA vaccine.
Map:
Every virus has signature features on its surface that can trigger your immune
system. Once the features are mapped, an mRNA vaccine provides the blueprint to create the defense that
can help your body protect itself if it encounters the virus.
Read:
Once your body has the blueprint, it knows exactly what to do. It reads mRNA
strands to build a defense by producing antibody proteins that are a lot like the answer key to a test.
This means the next time your immune system encounters this type of virus, it already has the answer to
help protect you.
Neutralize:
Your body now knows how to neutralize the virus and is able to defend
itself against the threat if it encounters the virus in the future. The message from the blueprint that
was read is retained and recalled when needed. It's like remembering the answer from an old test without
having to re-learn the material.
Activate:
Moderna is developing mRNA vaccines, like the investigational vaccine
mRNA-1647, that deliver blueprints to create the proteins that help activate immune responses against
a variety of viruses.
Vaccines aim to safely protect people against infections, and clinical trials are vital to creating vaccines. A clinical Trial can help researchers understand whether an investigational vaccine is safe and effective. By participating in the CMVictory Trial, you can help create a future where we may hopefully declare victory and prevent the spread of CMV.
Moderna is committed to keeping people at the center of everything we do as we continue to explore what is possible through mRNA science. Without people like you, researching potential new treatments and mRNA vaccines would not be possible.
We are proud to partner with the following groups and organizations in the fight for victory against CMV:
Clinical trial staff will explain any additional requirements and answer any questions you or a loved one may have about participation. You may stop participation in the clinical trial at any time, and you do not have to give a reason for doing so.
Moderna is committed to researching safe and effective mRNA-based vaccines and therapies to bring better health and living to people of all ages, sexes, and backgrounds.
The CMVictory Trial will take place at locations (or sites) all around the world. Use this site locator to search for the site closest to you—as well as their contact information.
The University of Melbourne
Carlton, Australia 3010
SEC Clinical Research LLC - Dothan - ClinEdge
Dothan, Alabama United States 36305
University of Alberta Hospital
Edmonton, Alberta Canada T6G 2B7
Applied Research Center of Arkansas
Little Rock , AR United States 72212
Hope Research Institute LLC - Peoria
Peoria, Arizona United States 85381
Hope Research Institute LLC - Hunt - Phoenix
Phoenix, Arizona United States 85018
Hope Research Institute LLC - Hunt - Tempe
Tempe, Arizona United States 85284
Noble Clinical Research - Tuscon
Tucson, Arizona United States 85704
Chandler Clinical Trials, LLC
Chandler, Arizona United States 85224
Preferred Research Partners - Little Rock
Little Rock, Arkansas United States 72211
Baptist Health Center for Clinical Research - Little Rock
Little Rock, Arkansas United States 72205
Paratus Clinical Research - Canberra
Bruce, Australian Capital Territory Australia 2617
Arizona Clinical Trials
Messa, AZ USA 85210
Care Access Research - Salt Lake City
Santa Clarita, CA United States 91321
Long Beach Research Institute, LLC
Long Beach, California USA 03300
Women’s Healthcare Research
San Diego, California United States 92111
Paradigm Clinical Research Institute - La Mesa
La Mesa, California United States 91942
Clinical Trials Management Services, LLC - Thousand Oaks
Thousand Oaks, California USA 91360
Velocity Clinical Research - La Mesa
La Mesa, California United States 91942
Velocity Clinical Research - Chula Vista
Chula Vista, California United States 91911
Next Level Clinical Trials
West Covina, California United States 91790
Paradigm Clinical Research - Redding
Redding, California United States 96001
Bayview Research Group - Valley Village
Valley Village, California United States 91607
Velocity Clinical Research - Banning
Banning, California United States 92220
Care Access Research - Salt Lake City
Aurora, CO United States 80012
Paradigm Clinical Research Institute Inc - ClinEdge - PPDS
Wheat Ridge, Colorado United States 80033-6109
Clinical Research Consultants - Milford
Milford, Connecticut United States 06460
Indago Research and Health Center - Hialeah
Hialeah, Florida United States 33012
Precision Clinical Research - Sunrise
Sunrise, Florida United States 33351
Riverside Clinical Research - Edgewater
Edgewater, Florida United States 32132
CVS Health Hub - Kennesaw
Kennesaw, Georgia United States 30152
Tekton Research - Chamblee
Chamblee, Georgia United States 30341
CVS Health Hub - Mcdonough
McDonough, Georgia United States 30253
CVS Health Hub - Dacula
Dacula, Georgia United States 30019
CVS Health Hub - Atlanta
Atlanta, Georgia United States 30329
CVS Health Hub - Newnan
Newnan, Georgia United States 30265
CVS Health Hub - Savannah
Savannah, Georgia United States 31405
CVS Health Hub - Atlanta/ MLK
Atlanta, Georgia United States 30311
iResearch Atlanta - Decatur
Decatur, Georgia United States 30030
Velocity Boise
Meridian, ID United States 86342
Affinity Health - Oak Brook
Oak Brook, IL United States 60523
ASHA Clinical Reseach
Hammond, IN United States 46324
Iowa Clinic - West Des Moines
West Des Moines, Iowa United States 50233
Heartland Research - Newton
Newton, Kansas United States 67114
Johnson County Clinical Trials - Lenexa
Lenexa, Kansas United States 66219
Alliance for Multispecialty Research - Lexington
Lexington, Kentucky United States 40509
MedPharmics - Metaire
Metairie, Louisiana United States 70006
Skylight Health Research – Burlington
Burlington, MA United States 01803
Meridian Clinical Research - Rockville
Rockville, Maryland United States 20854
ActiveMed Practices & Research - Methuen
Methuen, Massachusetts United States 01844
Great Lakes Research Institute
Southfield, MI United States 48075
University of Minnesota - Minneapolis
Minneapolis, Minnesota United States 55454
Clinical Research Institute - Minneapolis
Minneapolis, Minnesota United States 55402
MediSync Clinical Research Hattiesburg Clinic - Petal
Petal, Mississippi United States 39465
MedPharmics - Gulfport
Gulfport, Mississippi United States 39503
Boeson Research MSO - Missoula
Missoula, Montana USA 59804
Meridian Clinical Research - Hastings
Hastings, Nebaska United States 68901
Meridian Clinical Research - Omaha
Omaha, Nebraska United States 68114
Quality Clinical Research - Omaha
Omaha, Nebraska United States 68114
Meridian Clinical Research - Norfolk
Norfolk, Nebraska United States 68701
Meridian Clinical Research - Grand Island
Grand Island, Nebraska United States 68803
Albuquerque Clinical Trials - Albuquerque
Albequerque, New Mexico United States 87102
MedPharmics - Albuquerque
Albuquerque, New Mexico United States 87102
Paratus Clinical Research - Western Sydney
Kanwal, New South Wales Australia 2259
Paratus Clinical Research - Central Coast
Kanwal, New South Wales Australia 2259
Meridian Clinical Research - Endwell
Binghamton, New York United States 13901
Rochester Clinical Research - Rochester
Rochester, New York United States 14609
OnSite Clinical Solutions - Charlotte
Charlotte, North Carolina United States 28277
M3 Wake Research - Raleigh
Raleigh, North Carolina United States 27612-8106
Lucas Research - Morehead City
Morehead City, North Carolina United States 28557
Lillestol Research - Fargo
Fargo, North Dakota United States 58104
PriMed Physicians - Dayton
Dayton, Ohio United States 45419
ClinOhio Research Services - Columbus
Columbus, Ohio United States 43213
CTI Clinical Research Center - Cincinnati
Cincinnati, Ohio United States 45212
Meridian Clinical Research - Cincinnati
Cincinnati, Ohio United States 45219
Aventiv Research - Columbus
Columbus, Ohio United States 43213
Tekton Research - Yukon
Yukon, Oklahoma United States 73099
Lynn Health Science Institute - Oklahoma City
Oklahoma City, Oklahoma United States 73112
LMC Manna Research - Burlington
Burlington, Ontario Canada L7M 4Y1
Dr. Anil K. Gupta Medicine Professional Corporation
Toronto, Ontario Canada M9V 4B4
Centricity Research - Toronto
Toronto, Ontario Canada M9W 4L6
LMC Manna Research - Levis
Levis, Quebec Canada G6W 0M5
LMC Manna Research - Point-Claire
Point-Claire, Quebec Canada H9R 4S3
LMC Manna Research - Mirabel
Mirabel, Quebec Canada J7J 2K8
Diex Recherche - Victoriaville
Victoriaville, Quebec Canada G6P 6P6
Coastal Carolina Research Center - Charleston
North Charleston, South Carolina United States 29405
Koncord Clinical Research
McAllen, Texas United States 78577
Synergy Group US - Missouri City
Missouri City, Texas United States 77459
ARC Clinical Research at Wilson Parke - Austin
Austin, Texas United States 78726
Clinical Trials of Texas - San Antonio
San Antonio, Texas United States 78229
Crossroads Clinical Research - Victoria
Victoria, Texas United States 77901
Diagnostics Research Group - San Antonio
San Antonio, Texas United States 78229
Village Health Partners Frisco Medical Village - Plano
Plano, Texas United States 75024
Tekton Research - Beaumont
Beaumont, Texas United States 77706
Global Medical Research
Dallas, Texas United States 75224
ARC Clinical Research at Wilson Parke - AustinARC Clinical Research
Austin, Texas United States 78745
UTMB Health Pediatric Primary Care - League City
League City, Texas United States 77573
Tekton Research - Austin
Austin, Texas United States 78745
ARC Clinical Research at Kelly Lane - Pflugerville
Pflugerville, Texas United States 78660
Velocity Clinical Research - Cedar Park
Cedar Park, Texas United States 78613
DM Clinical Research - ERN - PPDS
Tomball, Texas United States 77375
Premier Family Physicians - Austin
Austin, Texas United States 78735
Velocity Clinical Research - West Jordan
West Jordan, Utah United States 84088
Foothill Family Clinic - Salt Lake City
Salt Lake City, Utah United States 84121
Foothill Family Clinic - Salt Lake City
Salt Lake City, Utah United States 84109
Barwon Health
Geelong, Victoria Australia 3217
Health Research of Hampton Roads - Newport News
Newport News, Virginia United States 23606
York Clinical Research - Norfolk
Norfolk, Virginia United States 23510
David Ramstad Associates Research - Suffolk
Suffolk, Virginia United States 23435-3763
Seattle Clinical Research Center
Seattle, Washington United States 98105
